i never went as far as methotrexate and infliximab infusions. just how bad was your psoriasis? i must have a mild case i have it on my arms legs stomach back behind hips and soon i will see if i have it in my bones. when steroid creams didn't help me i went looking for any cream that would ease the itching and help lessen the lesions. my psoriasis is due to stress. for 3 years i tried everything over the counter and like i said some steroid creams. i even plastered myself with zinc oxide, boy was that a mess. since you are having some issues it is good you have an appointment with your consultant. these symptoms you mention could be from the drug you are taking and not a flare up of psoriasis. your psoriasis must be really bad. i am sorry. i would talk to the doctor and see if you can slowly come off of the medications you are on to see if it is them causing your painful hands and wrists. i am sending you blessings that you will find help for your medical issues.